Polyphenols Sourced from Terrestrial and Marine Plants as Coronavirus Reproduction Inhibitors

The review presents the data of recent years concerning most important modern problem — search new inhibitors coronaviruses’ reproduction. Polyphenolic compounds (phlorotannins) from terrestrial and marine plants, polyvalent bioregulators with multiple biological activity, are considered as promising this type. Polyphenols able to interfere different stages life cycle. This fact characterizes polyphenols multipurpose drugs that affect vital proteins pathogens. At same time, authors draw attention many difficulties must be overcome develop medications based on plant polyphenols, since these characterized by complex structures, low bioavailability, well rapid excretion body. In addition, in vivo studies animals, clinical trials, required. Despite all difficulties, should eventually source for creating antiviral medicines, biologically active food additives, functional products.